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1

Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘- C -methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

Clark, Jeremy L., Hollecker, Laurent, Mason, J. Christian, Stuyver, Lieven J., Tharnish, Phillip M., Lostia, Stefania, McBrayer, Tamara R., Schinazi, Raymond F., Watanabe, Kyoichi A., Otto, Michael J.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 178 KB

english, 2005

2

Ventricular arrhythmias and the His–Purkinje system

Haissaguerre, Michel, Vigmond, Edward, Stuyvers, Bruno, Hocini, Meleze, Bernus, Olivier

Journal:

Nature Reviews Cardiology (formerly Nature Clinical Practice Cardiovascular Medicine)

Year:

2016

Language:

english

File:

PDF, 844 KB

english, 2016

3

Dioxygen: What Makes This Triplet Diradical Kinetically Persistent?

Borden, Weston Thatcher, Hoffmann, Roald, Stuyver, Thijs, Chen, Bo

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 508 KB

english, 2017

4

Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization

B. Robertson, G. Myers, C. Howard, T. Brettin, J. Bukh, B. Gaschen, T. Gojobori, G. Maertens, M. Mizokami, O. Nainan, S. Netesov, K. Nishioka, T. Shin-i, P. Simmonds, D. Smith, L. Stuyver, A. Weiner

Journal:

Archives of Virology

Year:

1998

Language:

english

File:

PDF, 81 KB

english, 1998

5

Mechanism of Activation of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

Murakami, E., Bao, H., Ramesh, M., McBrayer, T. R., Whitaker, T., Micolochick Steuer, H. M., Schinazi, R. F., Stuyver, L. J., Obikhod, A., Otto, M. J., Furman, P. A.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 205 KB

english, 2007

6

Back of the Envelope Selection Rule for Molecular Transmission: A Curly Arrow Approach

Stuyver, Thijs, Fias, Stijn, De Proft, Frank, Geerlings, Paul

Journal:

The Journal of Physical Chemistry C

Year:

2015

Language:

english

File:

PDF, 656 KB

english, 2015

7

Modeling our understanding of the His-Purkinje system

Vigmond, Edward J., Stuyvers, Bruno D.

Journal:

Progress in Biophysics and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 2.43 MB

english, 2015

8

Electrophilic Aromatic Substitution Reactions: Mechanistic Landscape, Electrostatic and Electric-Field Control of Reaction Rates and Mechanistic Crossovers

Stuyver, Thijs, Danovich, David, De Proft, Frank, Shaik, Sason

Journal:

Journal of the American Chemical Society

Year:

2019

Language:

english

File:

PDF, 6.08 MB

english, 2019

9

Do Diradicals Behave Like Radicals?

Stuyver, Thijs, Chen, Bo, Zeng, Tao, Geerlings, Paul, De Proft, Frank, Hoffmann, Roald

Journal:

Chemical Reviews

Year:

2019

Language:

english

File:

PDF, 10.90 MB

english, 2019

10

Unifying Conceptual Density Functional and Valence Bond Theory: The HardnessâSoftness Conundrum Associated with Protonation Reactions and Uncovering Complementary Reactivity Modes

Stuyver, Thijs, Shaik, Sason

Journal:

Journal of the American Chemical Society

Year:

2020

File:

PDF, 2.09 MB

2020

11

Serological and molecular analysis of hepatitis C virus envelope regions 1 and 2 during acute and chronic infections in chimpanzees

van Doorn, Leen-Jan, van Hoek, Kitty, de Martinoff, Guy, Bosman, Fons, Stuyver, Lieven, Kos, Ton, Frantzen, Inge, Sillekens, Peter, Maertens, Geert, Quint, Wim

Journal:

Journal of Medical Virology

Year:

1997

Language:

english

File:

PDF, 150 KB

english, 1997

12

Synthesis and Antiviral Evaluation of 2′,3′-Dideoxy-2′-fluoro-3′-C-hydroxymethyl-β-D-arabinofuranosyl Pyrimidine Nucleosides

Abdalla E. A. Hassan, Balakrina S. Pai, Stefania Lostia, Lieven Stuyver, Michael J. Otto, Raymond F. Schinazi, Kyoichi A. Watanabe

Journal:

Year:

2004

File:

PDF, 57 KB

2004

13

Synthesis of 5′-C-Methyl-1′,3′-dioxolan-4′-yl Nucleosides.

Jinfa Du, Steven Patterson, Junxing Shi, Byoung-Kwon Chun, Lieven J. Stuyver, Kyoichi A. Watanabe

Journal:

Year:

2004

File:

PDF, 126 KB

2004

14

Lymphoproliferative responses to hepatitis C virus core, E1, E2, and NS3 in patients with chronic hepatitis C infection treated with interferon alfa

G Leroux-Roels, C A Esquivel, R DeLeys, L Stuyver, A Elewaut, J Philippé, I Desombere, J Paradijs, G Maertens

Journal:

Year:

1996

Language:

english

File:

PDF, 278 KB

english, 1996

15

Three cases of severe subfulminant hepatitis in heart-transplanted patients after nosocomial transmission of a mutant hepatitis B virus

Lieven Stuyver, Sija De Gendt, Jean Fran Cadranel, Caroline Van Geyt, Georges Van Reybroeck, Richard Dorent, Iranj Gandjbachkh, Michel Rosenheim, Frederic Charlotte, Pierre Opolon, Jean Marie Huraux,

Journal:

Year:

1999

Language:

english

File:

PDF, 195 KB

english, 1999

16

Hepatitis B virus genotypes and HBsAg subtypes in refugees and injection drug users in the United States determined by LiPA and monoclonal EIA

Paul D. Swenson, Caroline Van Geyt, E. Russell Alexander, Holly Hagan, Jayne M. Freitag-Koontz, Shari Wilson, Heléne Norder, Lars O. Magnius, Lieven Stuyver

Journal:

Journal of Medical Virology

Year:

2001

Language:

english

File:

PDF, 159 KB

english, 2001

17

Rapid genotyping of hepatitis C virus RNA-isolates obtained from patients residing in Western Europe

G. E. M. Kleter, L. J. van Doorn, L. Stuyver, G. Maertens, J. T. Brouwer, S. W. Schalm, R. A. Heijtink, W. G. V. Quint

Journal:

Journal of Medical Virology

Year:

1995

Language:

english

File:

PDF, 883 KB

english, 1995

18

Significance of anti-hepatitis C virus core IgM antibodies in patients with chronic hepatitis C

Jean-Michel Pawlotsky, Françoise Darthuy, Jocelyne Rémiré, Claire Pellet, Laure Udin, Lieven Stuyver, Franqoise Roudot-Thoraval, Christophe Duvoux, Catherine Douvin, Ariane Mallat, Jean-Phillippe Mavi

Journal:

Journal of Medical Virology

Year:

1995

Language:

english

File:

PDF, 835 KB

english, 1995

19

HCV infection in a rural population of the Central African republic (CAR): Evidence for three additional subtypes of genotype 4

Dr. C. Fretz, D. Jeannel, L. Stuyver, V. Herve, F. Lunel, A. Boudifa, C. Mathiot, G. de Thé, J. J. Fournel

Journal:

Journal of Medical Virology

Year:

1995

Language:

english

File:

PDF, 302 KB

english, 1995

20

Synthesis and anti-viral activity of a series of d- and l-2′-deoxy-2′-fluororibonucleosides in the subgenomic HCV replicon system

Junxing Shi, Jinfa Du, Tianwei Ma, Krzysztof W. Pankiewicz, Steven E. Patterson, Phillip M. Tharnish, Tamara R. McBrayer, Lieven J. Stuyver, Michael J. Otto, Chung K. Chu, Raymond F. Schinazi, Kyoichi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 243 KB

english, 2005

21

Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

Jeremy L. Clark, J. Christian Mason, Laurent Hollecker, Lieven J. Stuyver, Phillip M. Tharnish, Tamara R. McBrayer, Michael J. Otto, Phillip A. Furman, Raymond F. Schinazi, Kyoichi A. Watanabe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

22

Synthesis of 5′,9-anhydro-3-(β-d-ribofuranosyl)xanthine, and 3,5′-anhydro-xanthosine as potential anti-hepatitis C virus agents

Byoung-Kwon Chun, Peiyuan Wang, Abdalla Hassan, Jinfa Du, Phillip M. Tharnish, Lieven J. Stuyver, Michael J. Otto, Raymond F. Schinazi, Kyoichi A. Watanabe

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 107 KB

english, 2005

23

Hepatitis B Virus: Genotypes and Subtypes in Brazilian Hemodialysis Patients

Sheila Araujo Teles, Regina Maria Bringel Martins, Bart Vanderborght, Lieven Stuyver, Ana Maria Coimbra Gaspar, Clara Fumiko Tachibana Yoshida

Journal:

Artificial Organs

Year:

1999

Language:

english

File:

PDF, 124 KB

english, 1999

24

A comparative analysis of HIV drug resistance interpretation based on short reverse transcriptase sequences versus full sequences

Kim Steegen, Michelle Bronze, Elke Van Craenenbroeck, Bart Winters, Koen Van der Borght, Carole L Wallis, Wendy Stevens, Tobias F Rinke de Wit, Lieven J Stuyver, the ART-A consortium

Journal:

AIDS Research and Therapy

Year:

2010

Language:

english

File:

PDF, 835 KB

english, 2010

25

Digital-imaging microscopy analysis of calcium release from sarcoplasmic reticulum in single rat cardiac myocytes

Michel Grouselle, Bruno Stuyvers, Simone Bonoron-Adele, Pierre Besse, Dinu Georgescauld

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1991

Language:

english

File:

PDF, 4.90 MB

english, 1991

26

Full genome sequence of three isolates of hepatitis C virus subtype 4b from Portugal

Diana Koletzki, Stéphanie Dumont, Hans Vermeiren, Paula Peixe, Jaime Nina, Ricardo J. Camacho, Lieven J. Stuyver

Journal:

Archives of Virology

Year:

2009

Language:

english

File:

PDF, 213 KB

english, 2009

27

Synthesis of 5′-C-methyl-1′,3′-dioxolan-4′-yl nucleosides

Jinfa Du, Steven Patterson, Junxing Shi, Byoung-Kwon Chun, Lieven J. Stuyver, Kyoichi A. Watanabe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 130 KB

english, 2004

28

Dynamics of viscoelastic properties of rat cardiac sarcomeres during the diastolic interval: involvement of Ca2+

Bruno D. M. Y. Stuyvers, Masahito Miura, Henk E. D. J. ter Keurs

Journal:

The Journal of Physiology

Year:

1997

Language:

english

File:

PDF, 491 KB

english, 1997

29

Hepatitis C virus in a hemodialysis unit: Molecular evidence for nosocomial transmission

Stuyver, Lieven, Claeys, Hendrik, Wyseur, Ann, Van Arnhem, Wouter, De Beenhouwer, Hans, Uytendaele, Stijn, Beckers, Jan, Matthijs, Dirk, Leroux-Roels, Geert, Maertens, Geert

Journal:

Kidney International

Year:

1996

File:

PDF, 637 KB

1996

30

Effect of stimulation rate, sarcomere length and Ca2+ on force generation by mouse cardiac muscle

Bruno D. Stuyvers, Andrew D. McCulloch, Jiqing Guo, Henry J. Duff, Henk E. D. J. ter Keurs

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 622 KB

english, 2002

31

Spatial Nonuniformity of Contraction Causes Arrhythmogenic Ca2+ Waves in Rat Cardiac Muscle

HENK E.D.J. TER KEURS, YUJI WAKAYAMA, MASAHITO MIURA, BRUNO D. STUYVERS, PENELOPE A. BOYDEN, AMIR LANDESBERG

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 1.08 MB

english, 2005

32

Role of Sarcomere Mechanics and Ca2+ Overload in Ca2+ Waves and Arrhythmias in Rat Cardiac Muscle

HENK E.D.J. TER KEURS, YUJI WAKAYAMA, YOSHINAO SUGAI, GUY PRICE, YUTAKA KAGAYA, PENELOPE A. BOYDEN, MASAHITO MIURA, BRUNO D.M. STUYVERS

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 461 KB

english, 2006

33

Sarcomere Mechanics in Uniform and Nonuniform Cardiac Muscle : A Link between Pump Function and Arrhythmias

Henk E.D.J. Ter Keurs, Tsuyoshi Shinozaki, Ying Ming Zhang, Yuji Wakayama, Yoshinao Sugai, Yutaka Kagaya, Masahito Miura, Penelope A. Boyden, Bruno D.M. Stuyvers, Amir Landesberg

Journal:

Annals of the New York Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 488 KB

english, 2008

34

Early Detection of Viral Resistance by Determination of Hepatitis B Virus Polymerase Mutations in Patients Treated by Lamivudine for Chronic Hepatitis B

Si Nafa, Si Ahmed, David Tavan, Christian Pichoud, Françoise Berby, Lieven Stuyver, Mark Johnson, Philippe Merle, Hassane Abidi, Christian Trépo, Fabien Zoulim

Journal:

Year:

2000

Language:

english

File:

PDF, 423 KB

english, 2000

35

Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region

Lieven J. Stuyver, Stephen A. Locarnini, Anna Lok, Douglas D. Richman, William F. Carman, Jules L. Dienstag, Raymond F. Schinazi

Journal:

Year:

2001

Language:

english

File:

PDF, 266 KB

english, 2001

36

Evaluation of a line probe assay for identification of hepatitis B virus precore variants in serum from chronic hepatitis B carriers

Charlotte L. Cameron-Wilson, Peter Muir, Anna L. Ballard, Sally Corden, Elizabeth H. Boxall, Erwin Sablon, Lieven Stuyver

Journal:

Journal of Virological Methods

Year:

2003

Language:

english

File:

PDF, 130 KB

english, 2003

37

HIV-1 coreceptor usage determination in clinical isolates using clonal and population-based genotypic and phenotypic assays

Kurt Van Baelen, Ina Vandenbroucke, Evelien Rondelez, Veerle Van Eygen, Hans Vermeiren, Lieven J. Stuyver

Journal:

Journal of Virological Methods

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

38

A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes

Kurt Van Baelen, Evelien Rondelez, Veerle Van Eygen, Kevin Ariën, Marleen Clynhens, Peggy Van den Zegel, Bart Winters, Lieven J. Stuyver

Journal:

Journal of Virological Methods

Year:

2009

Language:

english

File:

PDF, 443 KB

english, 2009

39

Arrhythmogenic Ca2+ release from cardiac myofilaments

Henk E.D.J. ter Keurs, Yuji Wakayama, Masahito Miura, Tsuyoshi Shinozaki, Bruno D. Stuyvers, Penelope A. Boyden, Amir Landesberg

Journal:

Progress in Biophysics and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 682 KB

english, 2006

40

Sarcomere mechanics in uniform and non-uniform cardiac muscle: A link between pump function and arrhythmias

Henk E.D.J. ter Keurs, Tsuyoshi Shinozaki, Ying Ming Zhang, Mei Luo Zhang, Yuji Wakayama, Yoshinao Sugai, Yutaka Kagaya, Masahito Miura, Penelope A. Boyden, Bruno D.M. Stuyvers, Amir Landesberg

Journal:

Progress in Biophysics and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.37 MB

english, 2008

41

Impact of Δ32-CCR5 heterozygosity on HIV-1 genetic evolution and variability—A study of 4 individuals infected with closely related HIV-1 strains

Kristen Chalmet, Filip Van Wanzeele, Els Demecheleer, Kenny Dauwe, Jolanda Pelgrom, Bea Van Der Gucht, Dirk Vogelaers, Jean Plum, Lieven Stuyver, Linos Vandekerckhove, Chris Verhofstede

Journal:

Year:

2008

Language:

english

File:

PDF, 883 KB

english, 2008

42

Ultra-Deep Sequencing of HIV-1 Reverse Transcriptase Before Start of an NNRTI-based Regimen in Treatment-naive Patients

Peter Messiaen, Chris Verhofstede, Ina Vandenbroucke, Sylvie Dinakis, Veerle Van Eygen, Kim Thys, Bart Winters, Jeroen Aerssens, Dirk Vogelaers, Lieven J. Stuyver, Linos Vandekerckhove

Journal:

Year:

2012

Language:

english

File:

PDF, 167 KB

english, 2012

43

Ca2+-dependence of diastolic properties of cardiac sarcomeres: involvement of titin

B.D. Stuyvers, M. Miura, J-P Jin, H.E.D.J. ter Keurs

Journal:

Progress in Biophysics and Molecular Biology

Year:

1998

Language:

english

File:

PDF, 452 KB

english, 1998

44

Comparison of the LiPA HIV-1 RT test, selective PCR and direct solid phase sequencing for the detection of HIV-1 drug resistance mutations

Jean-Claude Schmit, Lidia Ruiz, Lieven Stuyver, Kristel Van Laethem, Ilse Vanderlinden, Theresa Puig, Rudi Rossau, Jan Desmyter, Erik De Clercq, Bonaventura Clotet, Anne-Mieke Vandamme

Journal:

Journal of Virological Methods

Year:

1998

Language:

english

File:

PDF, 75 KB

english, 1998

45

Nosocomial transmission of hepatitis B virus associated with endomyocardial biopsy

Michel Rosenheim, Jean-François Cadranel, Lieven Stuyver, Richard Dorent, Franck Golliot, Pascal Astagneau, Vincent Di Martino, Annick Delcourt, Iradj Gandjbakhch, Jean-Marie Huraux, Françoise Lunel

Journal:

Gastroentérologie Clinique et Biologique

Year:

2006

File:

PDF, 1002 KB

2006

46

Hepatitis C virus (HCV) genotype analysis in apparently healthy anti- HCV-positive Parisian blood donors

L. Stuyver, C. Fretz, C. A. Esquivel, A. Boudifa, D. Jaulmes, N. Azar, F. Lunel, G. Leroux-Roels, G. Maertens, J. J. Fournel

Journal:

Transfusion (Wiley)

Year:

1996

Language:

english

File:

PDF, 789 KB

english, 1996

47

Analysis of the Putative E1 Envelope and NS4a Epitope Regions of HCV Type 3

L. Stuyver, W. Vanarnhem, A. Wyseur, R. Deleys, G. Maertens

Journal:

Biochemical and Biophysical Research Communications

Year:

1993

File:

PDF, 339 KB

1993

48

Cloning and Phylogenetic Analysis of the Core, E2, and NS3/NS4 Regions of the Hepatitis C Virus Type 5a

L. Stuyver, W. Vanarnhem, A. Wyseur, G. Maertens

Journal:

Biochemical and Biophysical Research Communications

Year:

1994

File:

PDF, 369 KB

1994

49

A Contiguous Physical Map of the Pericentromeric Region of Chromosome 21q between D21Z1 and D21S13E

Wim Van Hul, Guy Van Camp, Lieven Stuyver, Jean M. Delabar, Melvin G. McInnis, Andrew C. Warren, Stylianos E. Antonarakis, Christine Van Broeckhoven

Journal:

Year:

1993

File:

PDF, 397 KB

1993

50

Effect of Angiotensin II on Calcium Release Phenomena in Normal and Hypertrophied Single Cardiac Myocytes

Serge Sempé, Bruno Stuyvers, Liliane Tariosse, Gérard Gouverneur, Pierre Besse, Simone Bonoron-Adèle

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1994

File:

PDF, 467 KB

1994

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